Maturity onset diabetes

In 2004, it was estimated that 3.4 million people had died of the consequences of a raised fasting glycemia (11).

More than 80% of the deaths by diabetes occur in countries with weak or intermediate income.(12).

The Word Health Organisation provides that in 2030, diabetes will be the seventh cause of death in the world (13).

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The fall of testosterone's production plays a determining role in progression of matutity onset diabetes independently of regimen and exercise.

2012- High-normal Glucose Levels in Non-diabetic and Pre-diabetic Men Are Associated with Decreased Testosterone Levels. Young Shin, Eun Ki Park1, Byoung Jin Park, Jae Yong Shim, Hye Ree Lee. Korean J Fam Med. 2012;33:152-156 pdf. (download) (8)

1992- Georges Debled- Diabète et testostérone pdf. (9) download

A testosterone's property known since tens of years :

Reduction in androgens' production with age causes sugar intolerance and lead to maturity onset diabetes diabetes.

Chronic insufficiency of testosterone's production is the major cause of maturity onset diabetes after forty.

(1-2-3-4-5-6).

Favorable impact of testosterone on maturity onset diabetes was shown in 2001 by a precise scientific study.

(7) pdf.(download

Androgens support the cicatrization of diabetes' gangrenous toes.

Bibliography

1. LITTLE K. Interaction between catabolic and anabolic steroids. Curr. Ther. Res. 12 : 658-676, 1970.

2. ALOIA J.F. AND FIELD R.A. The effects of androgens and related substances on carbohydrate metabolism, lipid metabolism and diabetes mellitus. Pharmac. Ther. 1 : 241-257, 1976.

3. ANDO S., RUBENS R. AND ROTTIERS R. Androgen Plasma Levels in Male Diabetics. J. Endocrinol. Invest., 7 : 21-24, 1984.

4. MOELLER J. Cholesterol : 27 Springer-Verlag Berlin Heidelberg New York London Paris Tokyo 1987.

5. HARRIS M. AND ENTMACHER PS. Mortality from Diabetes, in Diabetes in America : NIH Publication, 85 : 1468 U.S. Government Printing Office1985.

6. WHO Study Group -Diabetes Mellitus : World Health Organization Technical Report Series 727 GENEVA 1985.

7. DOMINIQUE SIMON, MD, PHD, MARIE-ALINE CHARLES, MD, NAJIBA LAHLOU, MD, KHALIL NAHOUL, MD, JEAN-MICHEL OPPERT, MD, PHD, MICHE` LE GOUAULT-HEILMANN, MD, NICOLE LEMORT, BSC, NADINE THIBULT, BSC, EVELYNE JOUBERT, MD, BEVERLEY BALKAU, PHD, EVELINE ESCHWEGE, MD :
Androgen Therapy Improves Insulin Sensitivity and Decreases Leptin Level in Healthy Adult Men With Low Plasma Total Testosterone. DIABETES CARE, VOLUME 24, NUMBER 12, DECEMBER 2001

8. Jin Young Shin, Eun Ki Park1, Byoung Jin Park, Jae Yong Shim, Hye Ree Lee. High-normal Glucose Levels in Non-diabetic and Pre-diabetic Men Are Associated with Decreased Testosterone Levels. Korean J Fam Med. 2012;33:152-156

9. DEBLED G: Au-delà de cette limite votre ticket est toujours valable. ou Comment vaincre le vieillissement de l'homme.1992: 96-103. Albin Michel

10. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet, 2011, 378(9785):31–40.

11. Global health risks. Mortality and burden of disease attributable to selected major risks. Geneva, World Health Organization, 2009.

12. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med, 2006, 3(11):e442.

13. Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011.

History of andropause disease	Life maintenance system	A foundation of life maintenance system	Health in XXI^st century