Nervous depression

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It accounts for 100 million consultations a year worldwide. Aggravated by stress, it can announce future deterioration in the nervous system.

Sufficient Testosterone amount lowers the amount of M.A.O. (MONO AMINE OXYDASE) (3) naturally

Link to Parkinson's disease

2012 - TRT (Testosterone Replacement Therapy) may reduce depression symptoms in hypogonadal men, including middle-aged men and those using antidepressants (4) download pdf.

1992- Georges Debled. Dépression nerveuse et testosterone. Download pdf. (5)

The influence of testosterone on the nervous system is numerous.

In 1971, Harold Persky, a researcher from the National Institute of Mental Health of the U.S. Public Health Service, reported in the revue Psychosomatic Medicine the relation of psychological measures of aggression and hostility to testosterone production in man (1).

They are different plasma levels of testosterone in young men and older men. In a young man, there is a correlation between testosterone plasma levels and measures of aggression and hostility. This equation was not valid for older men.

RELATION OF PSYCHOLOGIC MEASURES OF AGGRESSION AND HOSTILITY TO TESTOSTERONE PRODUCTION IN MAN
Age	Plasma testosterone in nanograms / 100 ml	Réactions
22 (range17 - 28 )	685	+
45,1 (range 31 - 66 )	404	-

According to Persky H., Smith K.D. et Basu G.K.

In 1974, Joel Ehrenkrantz, from the Department of Psychiatry from the Yale University School of Medicine, New Haven, Connecticut, and his collaborators reported the correlation between testosterone plasma levels with aggressive behavior and social dominance in man (2).

PLASMA TESTOSTERONE : CORRELATION WITH AGGRESSIVE BEHAVIOR AND SOCIAL DOMINANCE IN MAN
Behavior	Plasma testosterone in nanograms /100 ml
not aggressive	599
socially dominant	836
aggressive	1 010

According Ehrenkrantz J, Bliss E. et Sheard M.H.

When you consider the statistics of deaths by accident of the National Centre for Health Statistics, you see immediately that, under 65 years, men are dying threefold more than women. After 65 years, the death rate is the same for women and men who have lost their male hormones and their aggressivity.

NUMBER OF DEATH BY ACCIDENT REGISTRATED IN U.S.A. IN 1982
Under 65 years		More than 65 years
Men	Women	Man	Woman
54 000	17 000	12 000	11 000

According to the National Center for Health Statistics, Vital Statistics Report, Final Mortality Statistics, 1982.

BRAIN DETERIORATION

Near Amsterdam, Dirck Swaab, from the Dutch Institute for Brain Research, has demonstrated the trophic influence of testosterone on rats' brains. Microscopic observations show a fine ramification of the brain's cells in young rats. Those ramifications disappear in old rats but reappear under the influence of testosterone pellets implanted under the skin. This phenomenon is probably the same in men.

Bibliography

1. PERSKY H., SMITH K.D. AND BASU G.K. Relation of Psychologic Measures of Aggression and Hostility to Testosterone Production in Man: Psychosomatic Medicine, 33 ; 3: 265-277, 1971.

2. EHRENKRANZ J., BLISS E. AND SHEARD M.H. Plasma Testosterone: Correlation with Aggressive Behavior and Social Dominance in Man. Psychosomatic Medicine, 36 ; 6 : 469-475, 1974.

3. KLAIBER E.L., BROVERMAN D.M., VOGEL W., KOBAYASHI Y. The use of steroid hormones in depression. In Psychotropic action of hormones. Proceedings of the World Congress of biological psychiatry. Buenos Aires. Argentina, September 1974. Spectrum publications I.N.C.

4.Khera M, Bhattacharya RK, Blick G, Kushner H, Nguyen D, Miner MM. The effect of testosterone supplementation on depression symptoms in hypogonadal men from the Testim Registry in the U.S. (TRiUS). Aging Male. 2012 Mar;15(1):14-21. Epub 2011 Nov 18.

5. DEBLED G: Au-delà de cette limite votre ticket est toujours valable. ou Comment vaincre le vieillissement de l'homme.1992.